Scientific Publications

Citizens of Science

In our quest to invent life-transforming medicines for people with serious diseases, we encourage our colleagues to publish their research in leading scientific journals.

The links on this page are not affiliated with Regeneron Pharmaceuticals, Inc. Links to sites outside of Regeneron are provided as a resource to the viewer. Regeneron accepts no responsibility for the content of linked sites.

Featured Publications
  • Early-Stage Research
  • Clinical Research
Aging
The Activin/FLRG pathway associates with poor COVID-19 outcomes in hospitalized patients

Published in Mol Cell Biol. 2021 Nov 1:MCB0046721. doi: 10.1128/MCB.00467-21. Online ahead of print.

Genetics
Gene-level analysis of rare variants in 379,066 whole exome sequences identifies an association of GIGYF1 loss of function with type 2 diabetes

Published in Sci Rep. 2021 Nov 3;11(1):21565. doi: 10.1038/s41598-021-99091-5.

Genetic and functional evidence links a missense variant in B4GALT1 to lower LDL and fibrinogen

Published in Science. 2021 Dec 3;374(6572):1221-1227. doi: 10.1126/science.abe0348. Epub 2021 Dec 2.

Exome sequencing and analysis of 454,787 UK Biobank participants

Published in Nature. 2021 Oct 18. doi: 10.1038/s41586-021-04103-z. Online ahead of print.

Immunology & Inflamation
Humanization of T cell-mediated immunity in mice

Published in Sci Immunol. 2021 Dec 17;6(66):eabj4026. doi: 10.1126/sciimmunol.abj4026. Epub 2021 Dec 17.

Obesity, Muscle & Metabolism
Muscle-secreted neurturin couples myofiber oxidative metabolism and slow motor neuron identity

Published in Cell Metab. 2021 Sep 23:S1550-4131(21)00422-8. doi: 10.1016/j.cmet.2021.09.003. Online ahead of print.

Technology
Identification of the specific causes of polysorbate 20 degradation in monoclonal antibody formulations containing multiple lipases

Published in Pharm Res. 2022 Jan 3. doi: 10.1007/s11095-021-03160-3. Online ahead of print.

High affinity human Fc specific monoclonal antibodies for capture kinetic analyses of antibody-antigen interactions

Published in Anal Biochem. 2021 Nov 14:114455. doi: 10.1016/j.ab.2021.114455. Online ahead of print.

AdRoit is an accurate and robust method to infer complex transcriptome composition

Published in Commun Biol. 2021 Oct 22;4(1):1218. doi: 10.1038/s42003-021-02739-1.

General Medicine
Compassionate Use of REGEN-COV ® in Patients with COVID-19 and Immunodeficiency-Associated Antibody Disorders

Published in Clin Infect Dis. 2021 Dec 31:ciab1059. doi: 10.1093/cid/ciab1059. Online ahead of print.

REGEN-COV(®) antibody cocktail bioanalytical strategy: comparison of LC-MRM-MS and immunoassay methods for drug quantification

Published in Bioanalysis. 2021 Dec;13(24):1827-1836. doi: 10.4155/bio-2021-0190. Epub 2021 Nov 8.

Population pharmacokinetics and exposure-response modeling for evinacumab in homozygous familial hypercholesterolemia

Published in CPT Pharmacometrics Syst Pharmacol. 2021 Sep 29. doi: 10.1002/psp4.12711. Online ahead of print.

Immunology & Inflamation
Efficacy and Safety of Itepekimab in Patients with Moderate-to-Severe Asthma

Published in N Engl J Med. 2021 Oct 28;385(18):1656-1668. doi: 10.1056/NEJMoa2024257.

Ophthalmology
Correlation of Change in Central Subfield Thickness and Change in Visual Acuity in Neovascular AMD: Post Hoc Analysis of VIEW 1 and 2

Published in Am J Ophthalmol. 2021 Nov 27:S0002-9394(21)00617-6. doi: 10.1016/j.ajo.2021.11.020. Online ahead of print.

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