Last Updated: June 2024
Headshot of Leonard S. Schleifer, MD, PhD, co-Founder, Board co-Chair, President and CEO.

Leonard Schleifer, MD, PhD

Board co-Chair, President and Chief Executive Officer
Leonard S. Schleifer, MD, PhD, has built and managed Regeneron since 1988 alongside his co-Founder George D. Yancopoulos. He is currently board co-chair, president and chief executive officer of Regeneron. 

Len discusses his motivation for starting the company.

Early Life and Inspiration

Len grew up in Queens, New York, with parents and teachers who sparked his passion for science and entrepreneurship from a young age. He earned his M.D. and Ph.D. in pharmacology from the University of Virginia and became a licensed physician certified in neurology. While working as a practicing neurologist and professor at Cornell Medical School, Len became frustrated with the lack of effective treatments for patients with serious neurodegenerative diseases like Parkinson’s and Alzheimer’s. He wondered if new biotechnologies could be harnessed to potentially make an impact for these people, their families and many others.

Regeneron Founding

Len founded Regeneron in 1988, with the vision of creating a company built entirely on science, where scientists are the heroes, and everyone works toward the common goal of helping patients. He knew he needed a top-notch team and immediately recruited George D. Yancopoulos, a top scientist from Columbia University, as co-Founder, along with Nobel Laureates to the Board of Directors. Len's dream is now a reality, and the Regeneron team is using its scientific prowess to consistently and repeatedly bring new medicines to people in need.

Scientific Innovation

Regeneron maintains the proud distinction of being one of the most innovative biotechnology companies in the world, with numerous FDA-approved medicines and product candidates in development, almost all of which are homegrown in the company’s laboratories. Regeneron's medicines and pipeline are designed to help patients with eye diseases, allergic and inflammatory diseases, cancer, cardiovascular and metabolic diseases, neurological diseases, hematologic conditions, infectious diseases, and rare diseases.

Regeneron is among the few pharmaceutical companies with the expertise and technologies to rapidly respond to global public health emergencies. The company pioneered the first effective antibody cocktail treatments for both COVID-19 and Ebola, collectively benefitting millions of people worldwide. In September 2025, Regeneron demonstrated its commitment to global health by announcing a donation of up to 500 doses of its Ebola treatment to the World Health Organization, specifically for use by governments in low- and lower-middle income countries. Simultaneously, the company rushed a delivery of doses and personal protection equipment (PPE) to the Democratic Republic of the Congo (DRC) to immediately address a rapidly escalating Ebola outbreak. These achievements, according to Len, are the result of decades of strategic investments in technologies that generate antibodies that, when directed toward a virus, could become an effective treatment approach.

The real healthcare problem

We are taking the long view by investing in innovation to tackle society's biggest health challenges.

A scientist working in a lab.

Corporate Responsibility

Inspired by his father’s words, “do well by doing good,” Len has consistently championed the integration of corporate responsibility into Regeneron’s core mission. This philosophy drives the company’s efforts to use its unique knowledge and expertise to benefit society, the economy and the environment. Regeneron’s approach prioritizes advancing scientific discovery, fostering a culture of integrity and excellence, and building sustainable communities. Regeneron invests heavily in STEM (science, technology, engineering and math) education efforts that fuel the next generation of scientific leaders.

Awards & Recognition

Under Len’s leadership, Regeneron has been lauded as a top company to work for by Science magazine, Fortune, Forbes, Fast Company, and others. It has also been recognized for its commitment to corporate responsibility through inclusion in the Dow Jones Sustainability Index and the Civic 50 list of most community-minded companies, among others. In recent years, Regeneron has also been recognized for its pandemic response by organizations including Fast Company’s World Changing Ideas.

In 2019, Len was elected as a fellow by the American Association for the Advancement of Science (AAAS). He has been recognized by Barron’s Best CEOs and as an Ernst & Young’s Entrepreneur of the Year, alongside Dr. Yancopoulos.

Reflecting on Achievements

For over 35 years, our mission has been to use the power of science to bring new medicines to patients. To achieve this, we seek to constantly improve the drug discovery and development process by applying our homegrown technologies, our deep understanding of science and our relentless spirit.

 Regeneron: Video featuring Regeneron’s co-Founder, Board co-Chair, President and CEO Len Schleifer, MD, PhD being interviewed.

Professional Experience

Co-Founder, President and Chief Executive Officer, Regeneron (1988-Present)

Chairman, Regeneron (1988-1995)

Clinical Professor of Neurology and Neuroscience, Department of Neurology, Weill Cornell Medical College (1992-Present)

Board co-Chair (2023-Present)

Education

Doctor of Philosophy in Pharmacology at University of Virginia

Doctor of Medicine in Pharmacology at University of Virginia

Bachelor of Arts at Cornell University

Highlights of Honors & Awards

Biotechnology Heritage Award, Science History Institute and Biotechnology Innovation Organization (2025)

Prix Galien Roy Vagelos Pro Bono Humanum Award (2021)

Crain’s New York Notables in Healthcare (2021)

Walter Reed Distinguished Achievement Award (2020)

Forbes America’s 100 Most Innovative Leaders (2019)

Cornell Entrepreneur of the Year (2019)

Legends in Leadership Award, Yale School of Management, CEO Institute (2017)

Ernst & Young Life Sciences Entrepreneurs of the Year National Award (2016)

Barron’s World’s Best CEOs (2016)

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An Unequivocal Victory for Innovation

A recent Supreme Court decision helps patients by protecting the scientific innovation emerging from America’s thriving biopharma community.

A machine in a laboratory.

The Regeneron Journey

Read our perspective on the rapid development and delivery of a COVID-19 treatment.

A scientist looking into a microscope.

Doing Well by Doing Good

View our Responsibility Report to learn how we address the issues that matter most to Regeneron's business and society in order to build resiliency and improve our world.