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2002 Publications
| Acute intensive insulin therapy exacerbates diabetic blood-retinal barrier breakdown via hypoxia-inducible factor-1alpha and VEGF Poulaki V, Qin W, Joussen AM, Hurlbut P, Wiegand SJ, Rudge J, Yancopoulos GD, Adamis AP J Clin Invest. 109(6):805-815 |
| Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by angiopoietin-1 Gale N, Thurston G, Hackett S, Renard R, Wang Q, McClain J, Martin C, Witte C, Witte M, Jackson D, Suri C, Campochiaro P, Wiegand S, Yancopoulos G Dev Cell. 3(3):411-23 |
| Angiopoietin-2 plays an important role in retinal angiogenesis Hackett SF, Wiegand S, Yancopoulos G, Campochiaro PA J Cell Physiol 192(2):182-7 |
| Binding of discoidin domain receptor 2 to collagen I: an atomic force microscopy investigation Agarwal G, Kovac L, Radziejewski C, Samuelsson SJ Biochemistry 41(37):11091-8 |
| Blockade of EphA Receptor Tyrosine Kinase Activation Inhibits Vascular Endothelial Cell Growth Factor-Induced Angiogenesis Cheng N, Brantley DM, Liu H, Lin Q, Enriquez M, Gale N, Yancopoulos G, Cerretti DP, Daniel TO, Chen J Mol Cancer Res 1(1):2-11 |
| Brain-derived neurotrophic factor triggers transcription-dependent, late phase long-term potentiation in vivo Messaoudi E, Ying SW, Kanhema T, Croll SD, Bramham CR J Neurosci 22(17):7453-61 |
| Calcineurin and skeletal muscle growth Yancopoulos GD, Glass DJ Nat Cell Biol. 4(3):E46-7 |
| Complementary actions of VEGF and angiopoietin-1 on blood vessel growth and leakage Thurston G J Anat 200(6):575-80 |
| Complementary and coordinated roles of the VEGFs and angiopoietins during normal and pathologic vascular formation Gale NW, Thurston G, Davis S, Wiegand SJ, Holash J, Rudge JS, Yancopoulos GD Cold Spring Harb Symp Quant Biol 67:267-73 |
| Dean Vortex Membrane Microfiltration and Diafiltration of rBDNF E. coli Inclusion Bodies Schutyser M, Rupp R, Wideman J, Belfort G Biotechnol Prog 18(2):322-9 |
| Discoidin domain receptor 2 (DDR2) interacts with Src and Shc following its activation by type I collagen. Ikeda K, Wang LH, Torres R, Zhao H, Olaso E, Eng Francis J, Labrador P, Klein R, Lovett D, Yancopoulos GD, Friedman SL, Lin HC J Biol Chem 277(21):19206-12 |
| Discoidin domain receptor 2 regulates fibroblast proliferation and migration through the extracellular matrix in association with transcriptional activation of matrix metalloproteinase-2 Olaso E, Labrador JP, Wang L, Ikeda K, Eng FJ, Klein R, Lovett DH, Lin HC, Friedman SL. J Biol Chem. 277(5):3606-13 |
| EphB ligand, ephrinB2, suppresses the VEGF- and angiopoietin 1-induced Ras/mitogen-activated protein kinase pathway in venous endothelial cells. Kim I, Ryu YS, Kwak HJ, Ahn SY, Oh JL, Yancopoulos GD, Gale NW, Koh GY. FASEB J 16(9):1126-8. |
| Heparan sulfate proteoglycans retain Noggin at the cell surface: a potential mechanism for shaping bone morphogenetic protein gradients Paine-Saunders S, Viviano BL, Economides AN, Saunders S J Biol Chem 277(3):2089-96 |
| Hemochorial placentation in the primate: expression of vascular endothelial growth factor, angiopoietins, and their receptors throughout pregnancy Wulff C, Wilson H, Dickson SE, Wiegand SJ, Fraser HM. Biol Reprod 66(3):802-12 |
| Mapping sites responsible for interactions of agrin with neurons Burgess RW, Dickman DK, Nunez L, Glass DJ, Sanes JR J Neurochem. 83(2):271-84 |
| Mechanisms which mediate the antiapoptotic effects of angiopoietin-1 on endothelial cells Harfouche R, Hassessian HM, Guo Y, Faivre V, Srikant CB, Yancopoulos GD, Hussain SN Microvasc Res. 64(1):135-47 |
| Mistargeting hippocampal axons by expression of a truncated Eph receptor. Yue Y, Chen ZY, Gale NW, Blair-Flynn J, Hu TJ, Yue X, Cooper M, Crockett DP, Yancopoulos GD, Tessarollo L, Zhou R. Proc Natl Acad Sci U S A. 99(16):10777-10782 |
| Potent VEGF blockade causes regression of coopted vessels in a model of neuroblastoma. Kim ES, Serur A, Huang J, Manley CA, McCrudden KW, Frischer JS, Soffer SZ, Ring L, New T, Zabski S, Rudge JS, Holash J, Yancopoulos GD, Kandel JJ, Yamashiro DJ Proc Natl Acad Sci U S A 99(17):11399-404 |
| Prevention of thecal angiogenesis, antral follicular growth, and ovulation in the primate by treatment with vascular endothelial growth factor Trap R1R2 Wulff C, Wilson H, Wiegand SJ, Rudge JS, Fraser HM Endocrinology 143(7):2797-807 |
| Recombinant angiopoietin-1 restores higher-order architecture of growing blood vessels in mice in the absence of mural cells Uemura A, Ogawa M, Hirashima M, Fujiwara T, Koyama S, Takagi H, Honda Y, Wiegand SJ, Yancopoulos GD, Nishikawa SI J Clin Invest 110(11):1619-1628 |
| Rgulation of vasculogenesis and angiogenesis by EphB/ephrin-B2 signaling between endothelial cells and surrounding mesenchymal cells Oike Y, Ito Y, Hamada K, Zhang XQ, Miyata K, Arai F, Inada T, Araki K, Nakagata N, Takeya M, Kisanuki YY, Yanagisawa M, Gale NW, Suda T Blood 100(4):1326-1333 |
| Retinal vascular endothelial growth factor induces intercellular adhesion molecule-1 and endothelial nitric oxide synthase expression and initiates early diabetic retinal leukocyte adhesion in vivo. Joussen AM, Poulaki V, Qin W, Kirchhof B, Mitsiades N, Wiegand SJ, Rudge J, Yancopoulos GD, Adamis AP. Am J Pathol. 160(2):501-9. |
| Ribonuclease activity and RNA binding of recombinant human Dicer Provost P, Dishart D, Doucet J, Frendewey D, Samuelsson B, Radmark O EMBO J 21(21):5864-5874 |
| Structural basis of BMP signalling inhibition by the cystine knot protein Noggin Groppe J, Greenwald J, Wiater E, Rodriguez-Leon J, Economides AN, Kwiatkowski W, Affolter M, Vale WW, Belmonte JC, Choe S Nature 420(6916):636-42 |
| Suppression of diabetic retinopathy with angiopoietin-1 Joussen AM, Poulaki V, Tsujikawa A, Qin W, Qaum T, Xu Q, Moromizato Y, Bursell SE, Wiegand SJ, Rudge J, Ioffe E, Yancopoulos GD, Adamis AP Am J Pathol. 160(5):1683-93 |
| VEGF-Trap: A VEGF blocker with potent antitumor effects Holash J, Davis S, Papadopoulos N, Croll SD, Ho L, Russell M, Boland P, Leidich R, Hylton D, Burova E, Ioffe E, Huang T, Radziejewski C, Bailey K, Fandl JP, Daly T, Wiegand SJ, Yancopoulos GD, Rudge JS Proc Natl Acad Sci U S A 99(17):11393-8 |