Peer Review of Research Assures Standards of Quality
1996 Publications
| A continuous striatal infusion of 6-hydroxydopamine produces a terminal axotomy and delayed behavioral effects Jones BE, Boylan CB, Fritsche M, Juhasz M, Jackson C, Wiegand SJ, Hyman C, Lindsay RM, Altar CA. Brain Res 709(2):275-84 |
| A double-blind placebo-controlled clinical trial of subcutaneous recombinant human ciliary neurotrophic factor (rHCNTF) in amyotrophic lateral sclerosis. ALS CNTF Treatment Study Group. ALS CNTF Treatment Study Group Neurology 46(5):1244-9 |
| A shared, non-canonical DNA conformation detected at DNA/protein contact sites and bent DNA in the absence of supercoiling or cognate protein binding Economides AN, Everdeen D, Panayotatos N J Biol Chem. 271(40):24836-41 |
| Agrin acts via a MuSK receptor complex Glass DJ, Bowen DC, Stitt TN, Radziejewski C, Bruno J, Ryan TE, Gies DR, Shah S, Mattsson K, Burden SJ, DiStefano PS, Valenzuela DM, DeChiara TM, Yancopoulos GD Cell 85(4):513-23 |
| Astrocytes infected with replication-defective adenovirus containing a secreted form of CNTF or NT3 show enhanced support of neuronal populations in vitro Smith GM, Hale J, Pasnikowski EM, Lindsay RM, Wong V, Rudge JS. Exp Neurol. 139(1):156-66 |
| BDNF down-regulates neurotrophin responsiveness, TrkB protein and TrkB mRNA levels in cultured rat hippocampal neurons Frank L, Ventimiglia R, Anderson K, Lindsay RM, Rudge JS Eur J Neurosci 8(6):1220-30 |
| BDNF enhances the functional reinnervation of the striatum by grafted fetal dopamine neurons Yurek DM, Lu W, Hipkens S, Wiegand SJ Exp Neurol. 137(1):105-18 |
| BDNF increases monoaminergic activity in rat brain following intracerebroventricular or intraparenchymal administration Siuciak JA, Boylan C, Fritsche M, Altar CA, Lindsay RM Brain Res. 710(1-2):11-20. |
| Bidirectional signalling through the EPH-family receptor Nuk and its transmembrane ligands Holland SJ, Gale NW, Mbamalu G, Yancopoulos GD, Henkemeyer M, Pawson T. Nature 383(6602):722-5 |
| Characterization of the responses of Purkinje cells to neurotrophin treatment Larkfors L, Lindsay RM, Alderson RF J Neurochem. 66(4):1362-73 |
| Ciliary Neurotrophic Factor Induces Down- Regulation of it's Receptor and Desensiization of Signal Transduction Pathways in Vivo: Non-Equivalence with Pharmacological Activity DiStefano PS, Boulton TG, Stark JL, Zhu Y, Adryan KM, Ryan TE, Lindsay RM. J. Biol. Chem 271:22839-22846. |
| Ciliary neurotrophic factor protects striatal output neurons in an animal model of Huntington disease Anderson KD, Panayotatos N, Corcoran TL, Lindsay RM, Wiegand SJ Proc Natl Acad Sci U S A 93(14):7346-51 |
| CNTF induces raphe neuronal precursors to switch from a serotonergic to a cholinergic phenotype in vitro Rudge JS, Eaton MJ, Mather P, Lindsay RM, Whittemore SR Mol Cell Neurosci. 7(3):204-21 |
| Degeneration of vestibular neurons in late embryogenesis of both heterozygous and homozygous BDNF null mutant mice Bianchi LM, Conover JC, Fritzsch B, DeChiara T, Lindsay RM, Yancopoulos GD Development 122(6):1965-73 |
| Detection of receptors for interleukin-6, interleukin-11, leukemia inhibitory factor, oncostatin M, and ciliary neurotrophic factor in bone marrow stromal/osteoblastic cells Bellido T, Stahl N, Farruggella TJ, Borba V, Yancopoulos GD, Manolagas SC J Clin Invest 97(2):431-7 |
| Differential activation of the extracellular signal-regulated kinase, Jun kinase and Janus kinase-Stat pathways by oncostatin M and basic fibroblast growth factor in AIDS-derived Kaposi's sarcoma cells Faris M, Ensoli B, Stahl N, Yancopoulos G, Nguyen A, Wang S, Nel AE AIDS 10(4):369-78 |
| Effects of BDNF and NT-4/5 on striatonigral neuropeptides or nigral GABA neurons in vivo Arenas E, Akerud P, Wong V, Boylan C, Persson H, Lindsay RM, Altar CA Eur J Neurosci 8(8):1707-17 |
| Effects of donor age and brain-derived neurotrophic factor on the survival of dopaminergic neurons and axonal growth in postnatal rat nigrostriatal cocultures Ostergaard K, Jones SA, Hyman C, Zimmer J Exp Neurol. 142(2):340-50 |
| Elk-L3, a novel transmembrane ligand for the Eph family of receptor tyrosine kinases, expressed in embryonic floor plate, roof plate and hindbrain segments. Gale NW, Flenniken A, Compton DC, Jenkins N, Copeland NG, Gilbert DJ, Davis S, Wilkinson DG, Yancopoulos GD. Oncogene 13:1343-1352 |
| Eph family receptors and their ligands distribute in opposing gradients in the developing mouse retina Marcus RC, Gale NW, Morrison ME, Mason CA, Yancopoulos GD Dev Biol 180(2):786-9 |
| Eph receptors and ligands comprise two major specificity subclasses and are reciprocally compartmentalized during embryogenesis. Gale NW, Holland SJ, Valenzuela DM, Flenniken A, Pan L, Ryan TE, Henkemeyer M, Strebhardt K, Hirai H, Wilkinson DG, Pawson T, Davis S, Yancopoulos GD. Neuron 17:9-19 |
| GDNF in a bind with known orphan: accessory implicated in new twist Lindsay RM, Yancopoulos GD. Neuron 17:571-574. |
| Implants of encapsulated human CNTF-producing fibroblasts prevent behavioral deficits and striatal degeneration in a rodent model of Huntington's disease. Emerich DF, Lindner MD, Winn SR, Chen EY, Frydel BR, Kordower JH. Journal of Neuroscience 16(16):5168-5181. |
| Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning. Davis S, Aldrich TH, Jones PF, Acheson A, Compton DL, Jain V, Ryan TE, Bruno J, Radziejewski C, Maisonpierre PC, Yancopoulos GD. Cell 87:1161-1169 |
| Local infusion of brain-derived neurotrophic factor modifies the firing pattern of dorsal raphe serotonergic neurons. Celada P, Siuciak JA, Tran TM, Altar CA, Tepper JM. Brain Res. 12:293 - 298 |
| Mice lacking brain-derived neurotrophic factor exhibit visceral sensory neuron losses distinct from mice lacking NT4 and display a severe developmental deficit in control of breathing. Erickson JT, Conover JC, Borday V, Champagnat J, Barbacid M, Yancopoulos G, Katz DM. 16(17): 5361-5371. |
| Neuroprotective Action of the Neurotrophins and CNTF in Vivo Pharmacology of Cerebral Ischemia Lindsay RM \Medpharm Scientific Publishers 465-475. |
| Neurotrophic Factors: Towards a Restorative Therapy of Parkinson's Disease Altar CA, Wiegand SJ, Lindsay RM, Cedarbaum JM Neuroprotection and Neurodegeneration 160-185 |
| Neurotrophin-4/5 maintains the cholinergic phenotype of axotomized septal neurons. Alderson RF, Wiegand SJ, Anderson KD, Cai N, Cho JY, Lindsay RM, Altar CA. European Journal of Neuroscience 8:282-290. |
| Non target-derived roles of the neurotrophins Acheson A, Lindsay RM. Philos Trans R Soc Lond B Biol Sci. 351:417-422. |
| Presence of Brain-Derived Neurotropic Factor in Brain and Human and Rat but not Mouse Serum Detected by a Sensitive and Specific Immunoassay” Radka, S.F., Holst, P.A., Fritsche, M., Altar, C.A. Brain Research 709:122-130. |
| Re: Pharmacokinetics and pharmacodynamics of rHCNTF in rodents. Cedarbaum JM, DeStefano PS, Lakings DB, Lindsay RM. Annals of Neurology 39(4):552. |
| Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis. Suri C, Jones PF, Patan S, Bartunkova S, Maisonpierre PC, Davis S, Sato TN, Yancopoulos GD. Cell 87:1171-1180 |
| Role of Neurotrophins and trk Receptors in the Development and Maintenance of Sensory Neurons: an Overview Lindsay, RM Phil. Trans. R. Soc. Long. B 351:365-373 |
| Six different cytokines that share GP130 as a receptor subunit, induce serum amyloid A and potentiate the induction of interleukin-6 and the activation of the hypothalamus-pituitary-adrenal axis by interleukin-1. Benigni F, Fantuzzi G, Sacco S, Sironi M, Pozzi P, Dinarello CA, Sipe JD, Poli V, Cappelletti M, Paonessa G, Pennica D, Panayotatos N, Ghezzi P. Blood 87:1851-1854. |
| Spontaneous Behaviours of Rats are Differentially Affected by Substantia Nigra Infursions of Brain-Derived Neurotrophic Factor and Neurotrophin-3 Martin-Iverson MT, Altar CA. Eur. J. Neurosci. 8:1696-1706 |
| Structural determinants of Trk receptor specificities using BDNF-based neurotrophin chimeras. Lai KO, Glass DJ, Geis D, Yancopoulos GD, Ip NY. Journal of Neuroscience Research 46:618-629. |
| The Amyotrophic Lateral Sclerosis Functional Rating Scale - Assessment of Activities of Daily Living in Patients With Amyotrophic Lateral Sclerosis ALS CNTF Treatment Study (ACTS) Phase I-II Study Group Archives of Neurology 53:141-147 |
| The hypothalamic ventromedial nucleus sends a met-enkephalin projection to the preoptic area's periventricular zone in the female rat. Hoffman GE, Dohanics J, Watson RE Jr, Wiegand SJ Brain Res Mol Brain Res. 36(2):201-10. |
| The Neurotrophins and CNTF: Two Families of Collaborative Neurotrophic Factors Ip, N.Y., Yancopoulos, G.D. Annual Review of Neuroscience 19:491-515. |
| The receptor tyrosine kinase MuSK is required for neuromuscular junction formation and is a functional receptor for agrin Glass DJ, DeChiara TM, Stitt TN, DiStefano PS, Valenzuela DM, Yancopoulos GD. Cold Spring Harbor Sym Quant Biol 85:501-512. |
| The receptor tyrosine kinase MuSK is required for neuromuscular junction formation in vivo DeChiara TM, Bowen DC, Valenzuela DM, Simmons MV, Poueymirou WT, Thomas S, Kinetz E, Compton DL, Rojas E, Park JS, Smith C, DiStefano PS, Glass DJ, Burden SJ, Yancopoulos GD. Cell 85:501-512 |
| Therapeutic Potential of the Neurotrophins and Neurotropin-CNTF Combinations in Peripheral and Neuropathies and Motor Neuron Disease Lindsay, RM Growth factors as drugs for neurological and sensory disorders (Ciba Foundation Symposia) 39-53 |