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1994 Publications

Antinociceptive effect of brain-derived neurotrophic factor and neurotrophin-3
Siuciak JA, Altar CA, Wiegand SJ, Lindsay RM
Brain Research
633:326-330
Arrest of motor neuron disease in wobbler mice cotreated with CNTF and BDNF
Mitsumoto H, Ikeda K, Klinkosz B, Cedarbaum JM, Wong V, Lindsay RM.
Science
265:1107-1110
Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components
Stahl N, Boulton TG, Farruggella T, Ip NY, Davis S, Witthuhn BA, Quelle FW, Silvennoinen O, Barbieri G, Pellegrini S, Ihle JN, Yancopoulos GD
Science
263:92-95
Brain-derived neurotrophic factor increases the electrical activity of pars compacta dopamine neurons in vivo
Shen RY, Altar CA, Chiodo LA.
Neurobiology
91:8920-8924
Characterization and crystallization of recombinant human neurotrophin-4
Fandl JP, Tobkes NJ, McDonald NQ, Hendrickson WA, Ryan TE, Nigam S, Acheson A, Cudny H, Panayotatos N
J Biol Chem
269(1): 755-759
Ciliary neurotrophic factor combined with soluble receptor inhibits synthesis of proinflammatory cytokines and prostaglandin-E2 in vitro
Shapiro L, Panayotatos N, Meydani SN, Wu D, Dinarello CA
Exp Cell Res
215(1):51-6
Ciliary neurotrophic factor enhances the survival of Purkinje cells in vitro.
Larkfors L, Lindsay RM, Alderson RF.
Eur J Neurosci
6:1015-102
Ciliary neurotrophic factor/leukemia inhibitory factor/interleukin 6/oncostatin M family of cytokines induces tyrosine phosphorylation of a common set of proteins overlapping those induced by other cytokines and growth factors.
Boulton TG, Stahl N, Yancopoulos GD.
J Biol Chem.
269(15):11648-11655
CNTF, FGF, and NGF collaborate to drive the terminal differentiation of MAH cells into postmitotic neurons
Ip NY, Boulton TG, Li Y, Verdi JM, Birren SJ, Anderson DJ, Yancopoulos GD.
Neuron
13:443-455
Diverse roles in neurotrophic factors in health and disease
Acheson A, Lindsay RM
Seminars in The Neurosciences
6:333-341
Effects of spreading depression and of brain-derived neurotrophic factor in cardiac arrest cerebral ischemia
N. Kawahara, C. A. Ruetzler, S. Wiegand, S. Cross, G. Mies, I. Klatzo
Pharmacology of Cerebral Ischemia
389-396
Efficacy of brain-derived neurotrophic factor and neurotrophin-3 on neurochemical and behavioral deficits associated with partial nigrostriatal dopamine lesions
Altar CA, Boylan CB, Fritsche M, Jones BE, Jackson C, Wiegand SJ, Lindsay RM, Hyman C
Journal of Neurochemistry
63(3):1021 - 1032
Fibroblast growth factor receptors have different signaling and mitogenic potentials
Wang JK, Gao G, Goldfarb M.
Mol Cell Biol
14:181-188.
In situ hybridization of trkB and trkC receptor mRNA in rat forebrain and association with high-affinity binding of [125I]BDNF, [125I]NT-4/5 and [125I]NT-3.
Altar CA, Siuciak JA, Wright P, Ip NY, Lindsay RM, Wiegand SJ.
Eur J Neurosci.
6:1389-140
LIFR beta and gp130 as heterodimerizing signal transducers of the tripartite CNTF receptor
Davis S, Aldrich TH, Stahl N, Pan L, Taga T, Kishimoto T, Ip NY, Yancopoulos GD
Science
260:1805-1808
Ligands for EPH-related receptor tyrosine kinases that require membrane attachment or clustering for activity.
Davis S, Gale NW, Aldrich TH, Maisonpierre PC, Lhotak V, Pawson T, Goldfarb M, Yancopoulos GD.
Science
266:816-819
Neural induction by the secreted polypeptide noggin.
Lamb TM, Knecht AK, Smith WC, Stachel SE, Economides AN, Stahl N, Yancopolous GD, Harland RM.
Science
262(5134):713-8.
Neurotrophic factor receptors and their signal transduction capabilities in rat astrocytes.
Rudge JS, Li Y, Pasnikowski EM, Mattsson K, Pan L, Yancopoulos GD, Wiegand SJ, Lindsay RM, Ip NY.
European Journal of Neuroscience
6:693-705
Neurotrophic factor receptors: just like other growth factor and cytokine receptors?
Ip NY, Yancopoulos GD.
Curr Opin Neurobiol
4:400-405
Neurotrophic factors and their receptors.
Ip NY, Yancopoulos GD.
Ann Neurol.
35:S13-S16
Neurotrophic factors: from molecule to man
Lindsay RM, Wiegand SJ, Altar CA, DiStefano PS.
Trends Neurosci
17(5):182-190
Neurotrophic Growth Factors and Neurodegenerative Diseases: Therapeutic Potential of the Neurotrophins and Ciliary Neurotrophic Factor
Lindsay RM
Neurobiology of Aging
15(2): 249-251
Neurotrophins and receptors
Lindsay RM
Prog Brain Res.
103:3-14
Overlapping and distinct actions of the neurotrophins BDNF, NT-3, and NT-4/5 on cultured dopaminergic and GABAergic neurons of the ventral mesencephalon
Hyman C, Juhasz M, Jackson C, Wright P, Ip NY, Lindsay RM
J Neurosci.
14(1):335-34
Recombinant human CNTF receptor alpha: production, binding stoichiometry, and characterization of its activity as a diffusible factor.
Panayotatos N, Everdeen D, Liten A, Somogyi R, Acheson A.
Biochemistry
33(19): 5813-5818
Regulation of ciliary neurotrophic factor in cultured rat hippocampal astrocytes.
Rudge JS, Morrissey D, Lindsay RM, Pasnikowski EM
Eur J Neurosci.
6:218-229
Regulation of neuropeptides in adult rat forebrain by the neurotrophins BDNF and NGF.
Croll SD, Wiegand SJ, Anderson KD, Lindsay RM, Nawa H
Eur J Neurosci.
6:1343-1353
Retrograde axonal transport of LIF is increased by peripheral nerve injury: correlation with increased LIF expression in distal nerve
Curtis R, Scherer SS, Somogyi R, Adryan KM, Ip NY, Zhu Y, Lindsay RM, DiStefano PS.
Neuron
12:191-204
Reversal of spatial memory impairments in aged rats by nerve growth factor and neurotrophins 3 and 4/5 but not by brain-derived neurotrophic factor.
Fischer W, Sirevaag A, Wiegand SJ, Lindsay RM, Bjorklund A.
Proc. Natl. Acad. Sci. USA
91:8607-8611
Similarities and differences in the way neurotrophins interact with the Trk receptors in neuronal and nonneuronal cells
Ip NY, Stitt TN, Tapley P, Klein R, Glass DJ, Fandl J, Greene LA, Barbacid M, Yancopoulos GD
Neuron
10:137-14
The alphas, betas, and kinases of cytokine receptor complexes
Stahl N, Yancopoulos GD.
Cell
74:587-590
The low affinity NGF receptor, p75, can collaborate with each of the Trks to potentiate functional responses to the neurotrophins.
Hantzopoulos PA, Suri C, Glass DJ, Goldfarb MP, Yancopoulos GD
Neuron
13:187-201v
The tripartite CNTF receptor complex: activation and signaling involves components shared with other cytokines.
Stahl N, Yancopoulos GD.
J Neurobiol.
25(11):1454-1466
Trophic protection of motor neurons: clinical potential in motor neuron diseases
Lindsay RM
J. Neurol, (Springer-Verlag)
241:S8-S11
Wobbler mouse motor neuron disease and neurotrophic factors
Mitsumoto H-i; Ikeda K, Wong V, Cedarbaum JM, Lindsay RM
ALS- from Charcot to the present and into the future
Chap. 25