Protein Production

Working in concert, the Regeneron Protein Expression, Process Development, and Industrial Operations groups have developed methods to significantly accelerate therapeutic protein development timelines in general, and development timelines for traps and antibodies in particular.

With regard to antibodies, Regeneron scientists have created a series of novel technologies that streamline and automate isolation of antigen-specific, antibody-producing cells; cloning of antibody gene sequences; and creation of cell lines capable of producing antibodies at very high levels. These technologies, coupled with the Regeneron extensive cell culture facilities for preclinical, clinical, and commercial manufacturing, enable the Company's engine for antibody development. Our team has a proven track record of taking lead candidates from gene cloning through scale-up of protein manufacturing to the 10,000 liter bioreactor scale.

 

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