Striving for new therapies that make patients' lives better

We have an extensive pipeline of investigational product candidates that are progressing through all stages of human clinical trials. Our product candidates address many serious medical conditions including cancer, eye diseases, inflammatory diseases, pain, cardiovascular diseases and allergic conditions.

Peter Powchik, M.D. Senior Vice President, Clinical Development "We have the enviable ability to add several additional fully human antibodies to the clinical pipeline each year due to the productivity of our discovery and development platforms."

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Product Candidate

Category Under Study

Sarilumab (REGN88)
IL-6R Antibody

Rheumatoid arthritis
Dupilumab (REGN668)
IL-4R Antibody
Atopic dermatitis in adults, asthma
RSV Antibody
Respiratory syncytial virus
Dupilumab (REGN668)
IL-4R Antibody
Atopic dermatitis in children,
nasal polyps in patients who
also have chronic sinusitis,
eosinophilic esophagitis

Sarilumab (REGN88)
IL-6R Antibody

Non-infectious uveitis
GDF8 Antibody
Skeletal muscle disorders
Fasinumab (REGN475)*
NGF Antibody
Pain due to osteoarthritis
*On partial clinical hold
PDGFR-beta Antibody + Aflibercept
Wet age-related macular degeneration
REGN1908-1909 Allergic disease
Evinacumab (REGN1500)
Angptl3 Antibody
Lipid disorders
Ang2 Antibody + Aflibercept
PD-1 Antibody
CD20/CD3 Antibody
GCGR Antibody

This section discusses pipeline drug candidates currently undergoing clinical testing in a variety of diseases. The safety and efficacy of these drug candidates have not been evaluated by any regulatory authorities for the indications described in this section.

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