Cancer remains one of the developed world’s most serious health problems despite recent advances. Beyond traditional chemotherapeutic approaches to treating cancer, one of the newer interventions is to selectively restrict the blood supply that feeds solid tumors.
Regeneron's approach in oncology is focused on anti-angiogenesis.
The growth of solid tumors requires the development of new blood vessels, a process called angiogenesis, to sustain the cancer by providing oxygen and nutrients. Regeneron's approach in oncology is focused on anti-angiogenesis - disrupting the flow of blood to tumors by binding particular proteins that stimulate the formation of new blood vessels.
We have several clinical-stage drug candidates in the pipeline that have been developed based on our understanding of angiogenesis.
REGN1979 is a bi-specific antibody that simultaneously targets CD20 and CD3 receptors on T-cells. Our bi-specific antibodies are developed using our VelociSuite technologies to target tumor antigens and T-cells receptors in order to harness the oncolytic properties of T-cells.